Search on: IMMUNOGLOBULIN LIGHT CHAINS, SURROGATE 
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Descriptor English:   Immunoglobulin Light Chains, Surrogate 
Descriptor Spanish:   Inmunoglobulina de Cadenas Ligeras Subrogadas 
Descriptor Portuguese:   Cadeias Leves Substitutas da Imunoglobulina 
Synonyms English:   Surrogate Immunoglobulin Light Chains
Surrogate Light Chains  
Tree Number:   D12.776.124.486.485.705.750.775
D12.776.124.486.485.950.750.500
D12.776.124.790.651.705.750.775
D12.776.124.790.651.950.750.500
D12.776.377.715.548.705.750.775
D12.776.377.715.548.950.750.500
D12.776.543.750.705.816.821.750.500
Definition English:   An immunolglobulin light chain-like protein composed of an IMMUNOGLOBULIN VARIABLE REGION-like peptide (such as light chain like lambda5 peptide) and an IMMUNOGLOBULIN CONSTANT REGION-like peptide (such as Vpreb1 peptide). Surrogate light chains associate with MU IMMUNOGLOBULIN HEAVY CHAINS in place of a conventional immunoglobulin light chains to form pre-B cell receptors. 
History Note English:   2008 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis BI biosynthesis
BL blood CF cerebrospinal fluid
CH chemistry CL classification
CT contraindications DU diagnostic use
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PD pharmacology
PH physiology PO poisoning
RE radiation effects TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   52787 
Unique Identifier:   D054444 

Occurrence in VHL:
 

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